HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N,N-Dimethyl-4-[6-(3-methyl-1H-4-pyrazolyl)-4-quinolyl]-1-piperazine sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | N,N-dimethyl-4-[6-(3-methyl-1-trityl-1H-pyrazolyl)-4-quinolyl]-1-piperazine sulfonamide | HCID 23537796 | — |
| Product | N,N-Dimethyl-4-[6-(3-methyl-1H-4-pyrazolyl)-4-quinolyl]-1-piperazine sulfonamide | HCID 178434512 | 69.4% |
Reaction Steps
37 mg N,N-dimethyl-4-[6-(3-methyl-1-trityl-1H-pyrazolyl)-4-quinolyl]-1-piperazine sulfonamide obtained in Example 183 and 0.2 mL trifluoroacetic acid were reacted in the same manner as in Example 165, to give 16 mg of the title compound as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074801B1 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-10d1169e32a1472798369eb75577d4b3 |
| Source note | uspto-grants-2006_07 |