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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 179274Generated: October 26, 2026

tert-Butanol → Trans-5-cyclopropyl-3-(2,6-dichloro-phenyl)-4-{4-[4-(4-methoxy-benzyloxy)-phenyl]-cyclohexyloxymethyl}isoxazole

https://huagongshe.com/reaction/179274

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-ButanolHCID 6386—
ReactantTetrahydrofuranHCID 8028—
Reactant18-Crown-6HCID 28557—
ReactantPotassiumHCID 5462222—
Reactant4-(Bromomethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazoleHCID 59369328—
Reactant4-[4-(4-Methoxy-benzyloxy)-phenyl]-cyclohexanolHCID 66905935—
ProductTrans-5-cyclopropyl-3-(2,6-dichloro-phenyl)-4-{4-[4-(4-methoxy-benzyloxy)-phenyl]-cyclohexyloxymethyl}isoxazoleHCID 66905992—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-f119f73fce6a405f9233646d23f692e2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)