Benzophenone imine → HCID 22025348, compound

HRID 1792852Notes

Reaction equation

HRID 1792852 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:5].[C:17](=N)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(Cl)Cl>[C:18]1([C:17](=[N:2][CH2:3][C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:5])[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 136809Benzophenone imineHCID 69630707HCID 69630707, compound

Product 1

HCID 22025348HCID 22025348, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Amino-N-(4-phenyl-butyl)-acetamide-hydrogen chloride salt is stirred with benzophenone imine (12.6 mL, 75 mmol) in CH2Cl2 (200 mL) for 24 h. The organics are then washed with water, dried (MgSO4), and concentrated to provide 2-(diphenylmethylenamino)-N-(4-phenyl-butyl)-acetamide (7) as a white solid which is used without further purification.

Workup

  1. washThe organics are then washed with water
  2. dry with materialdried (MgSO4)
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-0425835e9f904429b2a1ada31b068d43
Source dataset
uspto-grants-2006_07
Patent number
US07078425B2

Reaction notes

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