HCID 11046685, compound → HCID 11113481, compound

Participants

Reaction Steps

Iodide 6d (0.45 g; 1.1 mmol) was used as starting material. After cooling to rt, the reaction mixture was diluted with CH3OH and filtered. The filtrate was evaporated under vacuum, and the residue was recrystallized from CH3OH to afford 0.12 g (45%) of 1d as a white solid. mp>260 C; TLC (CH2Cl2-EtOAc, 1:1): Rf=0.51; 1H NMR (CDCl3): δ 0.88 (br t, 6H), 0.97 (t, 6H), 1.31 (br m, 12H), 1.60 (m, 4H), 1.72 (m, 4H), 3.06 (t, 4H), 3.38 (q, 4H), 7.00 (br t, 2H); 13C NMR (DMSO-d6): δ 14.2, 14.6, 22.8, 23.1, 26.9, 30.2, 31.7, 38.7, 131.3, 137.2, 163.5; UV/vis (CH3OH): max (M−1cm−1)=287 (26000), 295 (25900), 309 (14100); LRMS (CI+): m/z (%): 473 (100) [M+H]+; HRMS (CI+): calcd for C26H45N6O2 473.3604; found 473.3601; Anal. calcd for C26H44N6O2: C, 66.07; H, 9.38; N, 17.78; found: C, 66.26; H, 9.54; N, 17.83.

Provenance & Evidence