Nitric Acid → HCID 178514478, compound

HRID 1793281Notes

Reaction equation

HRID 1793281 reaction equation
[N:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]=[C:9]([OH:14])[C:8]([OH:15])=[N:7]2)=[N+:2]=[N-:3].[N+:16]([O-])([OH:18])=[O:17]>C(O)(=O)C>[N:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][C:13]=1[N+:16]([O-:18])=[O:17])[N:10]=[C:9]([OH:14])[C:8]([OH:15])=[N:7]2)=[N+:2]=[N-:3]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 178514481HCID 178514481, compound

Product 1

HCID 178514478HCID 178514478, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
24 °C

Procedure

2 g 6-azido-2,3-dihydroxyquinoxaline is suspended in 100 ml glacial acetic acid. To the suspension is added 16 ml fuming nitric acid at 24° C. The mixture is stirred at 24° C. for 4 h giving a precipitate of 1.9 g (78%) 6-azido-2,3-dihydroxy-7-nitroquinoxaline. IR: a peak at 2120 cm−1. NMR: two singlets (7.0 and 7.7 ppm downfield from TMS).

Workup

  1. additionTo the suspension is added 16 ml
  2. customat 24° C

Sources & evidence

ORD record
ord-a942e4fd4c9b4307850ab5026494e834
Source dataset
uspto-grants-2006_07
Patent number
US07081346B2

Reaction notes

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