3-Nitrophenylboronic Acid → 4,4-Dimethyl-6-(3-nitrophenyl)-1,4-dihydrobenzo[d][1,3]oxazin-2-one

Participants

Reaction Steps

4,4-Dimethyl-6-(3-nitrophenyl)-1,4-dihydro benzo[d][1,3]oxazin-2-one was prepared, from 6-iodo-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one and 3-nitrophenyl boronic acid according to the procedure of Example 4, as a yellowish solid: mp 244–245° C.; 1H-NMR (DMSO-d6) δ 10.38 (s, 1H, D2O exchangeable), 8.47 (s, 1H), 8.14–8.20 (m, 2H), 7.70–7.76 (m, 3H), 7.01 (d, 1H, J=8.1 Hz), 1.68 (s, 6H); MS (EI) m/z 297([M−H]−, 100%); Anal. Calc. For C16H14N2O4: C, 64.42, H, 4.73, N, 9.39. Found: C, 63.93, H, 4.91, N, 8.71.

Provenance & Evidence