HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Fluoro-4-methoxyphenyl)boronic acid → HCID 23541940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Fluoro-4-methoxyphenyl)boronic acid | HCID 15789384 | — |
| Reactant | Tert-butyl (6aS,10aR)-2-bromo-4,5,7,8,10,10a-hexahydropyrido[4,3-b]pyrrolo[3,2,1-hi]indole-9(6aH)carboxylate | HCID 20577007 | — |
| Product | HCID 23541940 | HCID 23541940 | 55% |
Reaction Steps
Tert-butyl(6aS,10aR)-2-(2-fluoro-4-methoxyphenyl)-4,5,7,8,10,10a-hexahydropyrido[4,3-b]pyrrolo[3,2,1-hi]indole-9(6aH)-carboxylate (116 mg, 55%) was prepared by the method of Example 89 step C from tert-butyl(6aS,10aR)-2-bromo-4,5,7,8,10,10a-hexahydropyrido[4,3-b]pyrrolo[3,2,1-hi]indole-9(6aH)-carboxylate (189 mg, 0.5 mmol) and 2-fluoro-4-methoxyphenylboronic acid (158 mg, 1.0 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07081455B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-c6582830226047c181cb50d2e39a90aa |
| Source note | uspto-grants-2006_07 |