Butyl bromide → HCID 86593172, compound

Participants

Reaction Steps

The title compound was prepared by the method of Example 382 as a yellow oil (28 mg, 82%) from (±)-cis-2-(2,3-dichlorophenyl)-5,6,7a,8,9,10,11,11a-octahydro-4H-pyrido[3′,4′:4,5]pyrrolo[3,2,1-ij]quinoline (30 mg, 0.083 mmol) and 1-bromobutane (23 mg, 0.17 mmol). 1H NMR (CDCl3, 300 MHz) δ 0.92(t, J=7.3 Hz, 3H), 1.32 (se, J=7.3 Hz, 2H), 1.53–1.65 (br, 2H), 2.02–2.25 (m, 5H), 2.38–2.53 (br, 2H), 2.58–2.68 (m, 1H), 2.75 (t, J=6.4 Hz, 2H), 2.80–2.92 (br, 1H), 2.95–3.07 (br, 1H), 3.31 (dt, J=10.3, 3.6 Hz, 1H), 3.37–3.45 (br, 2H), 6.94 (s, 1H), 6.99 (s, 1H), 7.15–7.21 (m, 2H), 7.35–7.40 (m, 1H) ppm.

Provenance & Evidence