HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 69593397, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 69593395 | HCID 69593395 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69593397 | HCID 69593397 | 88.4% |
Reaction Steps
5-(3,4-Dichloro-benzylidene)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester (0.45 g) was stirred under 1 atm of H2 in 20 ml of 1:1 of EtOH:EtOAc in the presence of PtO2 for 20 min. The reaction mixture was filtered through celite and concentrated to give 0.4 g of 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester (M+: 369).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07081531B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-ce628456443e443baa5b2213a7275376 |
| Source note | uspto-grants-2006_07 |