Sulfuric Acid → N-methyl perfluoro-1-ethane sulfonamide

Participants

Reaction Steps

C2F5SO2N(CH3)CH2CH2OH was prepared from C2F5SO2F by reaction with monomethylamine in MTBE, followed by stripping of the solvent, acidification with 19% sulfuric acid, then water washing and distillation at 5.5 mm at a head temperature of 69° C. to give C2F5SO2N(CH3)H. The C2F5SO2N(CH3)H was then reacted with 3 equivalents of ethylene carbonate and 0.08 equivalents K2CO3 neat at 110° C. overnight. The product was isolated by successive washes with water, 3% sulfuric acid and water, followed by distillation at 0.5 mm at a head temperature of 98° C.

Provenance & Evidence