3-Hydroxybenzoic Acid → HCID 178420834, compound

Participants

Reaction Steps

In a conical flask, cold absolute ethanol (ca. 40 ml) was added to 99% pure 3-hydroxybenzoic acid (1.8495 g; 13.39 mmol). Dissolution of the acid was achieved at room temperature by constant stirring. Morpholine (1.1653 g, 13.39 mmol) was added dropwise to the acid solution. The reaction was exothermic and some white fumes were observed; the turbid white solution of the acid turned yellow on addition of the colourless morpholine. The opening of the conical flask was covered with parafilm which was then punctured to allow slow evaporation of the solvent at room temperature. Transparent white polyhedral crystals of morpholinium 3-hydroxybenzoate were formed within 24 hrs. The crystals were filtered and washed with small aliquots of cold ethanol. Yield >70% (not optimised).

Provenance & Evidence