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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1793903Generated: November 4, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(2-fluorophenyl)pyrimidin-4-amine

https://huagongshe.com/reaction/1793903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant2-FluorobenzamidineHCID 4323059—
Product5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(2-fluorophenyl)pyrimidin-4-amineHCID 10215628—

Reaction Steps

The title compound, MS: m/e=363.0 (M+H+), was prepared from 2-fluorobenzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07022718B2
Source datasetuspto-grants-2006_04
ORD IDord-c8c834a32dc241548f12c79d28bc399e
Source noteuspto-grants-2006_04