Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1793908Generated: October 26, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amine

https://huagongshe.com/reaction/1793908

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant4-MethoxybenzenecarboximidamideHCID 229074—
Product5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amineHCID 10172601—

Reaction Steps

The title compound, MS: m/e=375.3 (M+H+), was prepared from 4-methoxybenzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07022718B2
Source datasetuspto-grants-2006_04
ORD IDord-99056677fffe4e6c86195c2b44cd2722
Source noteuspto-grants-2006_04