Ethyl 4-(tributylstannyl)benzoate → 4-Bicyclo[3.2.1]oct-2-en-2-yl-benzoic acid ethyl ester

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Reaction Steps

4-(Tri-n-butyl-stannyl)-benzoic acid ethyl ester of Example 15, Step A (1.82 g, 4.15 mmol) and bicyclo[3.2.1]oct-2-en-2-yl trifluoromethanesulfonate (1.17 g, 4.57 mmol) were reacted in the manner of Example 15, Step B. Purification by flash column chromatography on silica gel, eluting with a solvent gradient of from 0 to 10% ethyl acetate in hexane afforded the crude title compound a yellow oil.

Provenance & Evidence