HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 178473177, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | 1-(1,3-Thiazol-2-yl)ethan-1-ol | HCID 9989295 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178473177 | HCID 178473177 | 78.8% |
Reaction Steps
A mixture of 1-(2-thiazolyl)ethanol (1.17 g, 8.67 mmole) and ethyl bromoacetate (1.32 g, 8.63 mmole) was heated at 48 C for 18 hr. The reaction mixture was dissolved in acetonitrile (3 mL) and stored at 4 C. After 2 months the crystals which separated were filtered out and washed with 3:7 ether-acetonitrile to yield 2.028 g of the title compound, mp 101–103 C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07022721B1 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-3629852542604e20932501c0660ae383 |
| Source note | uspto-grants-2006_04 |