Methanol → HCID 86585991, compound

Participants

Reaction Steps

A solution of 86 mg (0.19 mmol) 4-(4-benzyloxy-benzylsulfanylcarbonyl)-piperazine-1-carboxylic acid tert-butyl ester in 2.2 ml 1.5M HCl/Et2O and 0.45 ml abs. MeOH was stirred at rt for 4 h. Evaporation of the reaction mixture provided 64 mg product as colourless powder. 1H-NMR(d6-DMSO): 3.03–3.17 m, 4H and 3.58–3.73 m, 4H; 4.09 s, 2H; 5.08 s, 2H; 6.95 d, J=7.5 Hz, 2H and 7.26 d, J=7.5 Hz, 2H (AB-system) and 7.30–7.50 m, 5H; 9.2 br, 2H. MS (ISP): 343.2 (M+H)+.

Provenance & Evidence