Morpholine → HCID 69141997, compound

Participants

Reaction Steps

Prepared in analogy to piperazine-1-carboxylic acid 4-benzyloxy-benzyl ester (Example 41) from piperazine-1,4-dicarboxylic acid 9H-fluoren-9-ylmethyl ester 4-(4-fluoro-benzyloxy)-benzyl ester and morpholine: colourless, waxy solid: IR (Nujol): 3341 cm−1, 1689 cm−1. 1H-NMR (CDCl3): 1.75 br, 1H; 2.85–2.90 m, 4H and 3.40–3.55 m, 4H; 5.02 s, 2H; 5.07 s, 2H; 6.94 d, J=8.4 Hz, 2H, 7.07 t, J=8.8 Hz, 2H, 7.30 d, J=8.4 Hz, 2H and 7.38–7.42 m, 2H. MS (EI): 344.3 M+.

Provenance & Evidence