Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate → HCID 86585997, Verbindung

HRID 1794078Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1794078
C(OC(N1CCN([C:14]([Cl:16])=[O:15])CC1)=O)(C)(C)C.[C:17]([O:21][C:22]([N:24]1[C@H:29]([CH3:30])[CH2:28][NH:27][CH2:26][C@@H:25]1[CH3:31])=[O:23])([CH3:20])([CH3:19])[CH3:18]>>[C:17]([O:21][C:22]([N:24]1[C@H:29]([CH3:30])[CH2:28][N:27]([C:14]([Cl:16])=[O:15])[CH2:26][C@@H:25]1[CH3:31])=[O:23])([CH3:20])([CH3:18])[CH3:19]

Komponenten

3

Edukt 2

HCID 11334154Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylateHCID 21021901tert-Butyl (2R,6S)-2,6-dimethylpiperazine-1-carboxylate

Produkt 1

HCID 86585997HCID 86585997, Verbindung

Versuchsvorschrift

cis-4-chlorocarbonyl-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester was prepared in analogy to 4-chlorocarbonyl-piperazine-1-carboxylic acid tert-butyl ester from cis-2,6-dimethylpiperazine-1-carboxylic acid tert-butyl ester (A. Muehlebach, P. Pino, Helv. Chim. Acta 73, 839 (1990)) by a modified procedure of Rhone-Poulenc DE 25 50 111 (Rhone-Poulenc).

Quellen und Nachweise

ORD-Eintrag
ord-3f4b7cf75e6e4b368fcbed81c35bfe0a
Quelldatensatz
uspto-grants-2006_04
Patentnummer
US07022707B2

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