3-(Phenylmethoxy)benzenemethanol → HCID 69143757, compound

Participants

Reaction Steps

3-Benzyloxybenzyl cis-2,6-dimethylpiperazine-1-carboxylate hydrochloride was prepared from cis 1-chlorocarbonyl-2,6-dimethyl-4-tert-butoxycarbonylpiperazine and 3-benzyloxybenzyl alcohol according to the methods described for Examples 52 and 54 to give the product as a white solid (0.254 g, 65% overall); νmax (nujol)/cm−1 3320, 2684, 2587, 1716, 1694, 1599, 1415, and 1312; δH (400 MHz, DMSO-d6) 10.02 (1H, br), 9.27 (1H, br), 7.45–7.28 (6H, m), 7.01–6.94 (3H, m), 5.11 (2H, s), 5.09 (2H, s), 4.33 (2H, m), 3.15 (2H, d, J 13.2 Hz), 3.07 (2H, m), and 1.31 (6H, d, J 7.6 Hz).

Provenance & Evidence