HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxypropyl 4-methylbenzenesulfonate → 2-Chloro-6-fluoro-4-(3-methoxy-propoxy)-benzylalcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxypropyl 4-methylbenzenesulfonate | HCID 13522988 | — |
| Reactant | 3-Chloro-5-fluoro-4-(hydroxymethyl)phenol | HCID 22220009 | — |
| Product | 2-Chloro-6-fluoro-4-(3-methoxy-propoxy)-benzylalcohol | HCID 22219994 | 90% |
Reaction Steps
This compound was prepared from 3-chloro-5-fluoro-4-hydroxymethyl-phenol and toluene-4-sulfonic acid 3-methoxy-propyl ester according to the procedure described in Example 179 to give the product as a yellowish oil (382 mg, 90%); MS (EI): 248.1 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07022707B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-405fb21d16b84870a96b17efc960ac1d |
| Source note | uspto-grants-2006_04 |