1-[3-(Dimethylamino)propyl]piperazine → HCID 69642449, compound

HRID 1794174Notes

Reaction equation

HRID 1794174 reaction equation
[CH3:1][N:2]([CH3:12])[CH2:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1.[ClH:13].[CH2:14]([O:16][C:17]1[CH:18]=[C:19]([C:26]2[C@@H:35]3[C@@H:30]([CH2:31][CH:32]=[CH:33][CH2:34]3)[C:29](=[O:36])[N:28]([C:37]3[CH:42]=[CH:41][C:40]([C:43](N4CCN(C5C=CC=CC=5)CC4)=[O:44])=[CH:39][CH:38]=3)[N:27]=2)[CH:20]=[CH:21][C:22]=1[O:23][CH2:24][CH3:25])[CH3:15]>C(OCC)C>[ClH:13].[ClH:13].[CH2:14]([O:16][C:17]1[CH:18]=[C:19]([C:26]2[C@@H:35]3[C@@H:30]([CH2:31][CH:32]=[CH:33][CH2:34]3)[C:29](=[O:36])[N:28]([C:37]3[CH:38]=[CH:39][C:40]([C:43]([N:9]4[CH2:8][CH2:7][N:6]([CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:12])[CH2:11][CH2:10]4)=[O:44])=[CH:41][CH:42]=3)[N:27]=2)[CH:20]=[CH:21][C:22]=1[O:23][CH2:24][CH3:25])[CH3:15]

Participants

4

Reactant 2

HCID 27362341-[3-(Dimethylamino)propyl]piperazineHCID 69641867HCID 69641867, compound

Product 1

HCID 69642449HCID 69642449, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Prepared from intermediate product A1 and 1-(3-dimethylaminopropyl)piperazine as described for compound 1. Cystallised from diethyl ether as the free base. M.p. 248° C. (with decomposition).

Sources & evidence

ORD record
ord-09ca7736f2074452920ce4ad893f872c
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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