1-(2-Furoyl)piperazine → HCID 69642373, compound

HRID 1794175Notes

Reaction equation

HRID 1794175 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7].Cl.[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:43]=[CH:42][C:41]([C:44](N4CCN(C5C=CC=CC=5)CC4)=[O:45])=[CH:40][CH:39]=3)[N:28]=2)[CH:21]=[CH:22][C:23]=1[O:24][CH2:25][CH3:26])[CH3:16]>C(OCC)C>[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:39]=[CH:40][C:41]([C:44]([N:11]4[CH2:10][CH2:9][N:8]([C:6]([C:2]5[O:1][CH:5]=[CH:4][CH:3]=5)=[O:7])[CH2:13][CH2:12]4)=[O:45])=[CH:42][CH:43]=3)[N:28]=2)[CH:21]=[CH:22][C:23]=1[O:24][CH2:25][CH3:26])[CH3:16]

Participants

4

Reactant 2

HCID 5502061-(2-Furoyl)piperazineHCID 69641867HCID 69641867, compound

Product 1

HCID 69642373HCID 69642373, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Prepared from intermediate product A1 and 1-(furan-2-yl-methanoyl)piperazine as described for compound 1. Cystallised from diethyl ether as the free base. M.p. 114–115° C.

Sources & evidence

ORD record
ord-d5d51fc169744796926f8c66106d317b
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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