1-Piperazinecarboxylic acid, ethyl ester → HCID 69641980, compound

HRID 1794177Notes

Reaction equation

HRID 1794177 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])[CH3:2].Cl.[CH2:13]([O:15][C:16]1[CH:17]=[C:18]([C:25]2[C@@H:34]3[C@@H:29]([CH2:30][CH:31]=[CH:32][CH2:33]3)[C:28](=[O:35])[N:27]([C:36]3[CH:41]=[CH:40][C:39]([C:42](N4CCN(C5C=CC=CC=5)CC4)=[O:43])=[CH:38][CH:37]=3)[N:26]=2)[CH:19]=[CH:20][C:21]=1[O:22][CH2:23][CH3:24])[CH3:14]>C(OCC)C>[CH2:1]([O:3][C:4]([N:6]1[CH2:7][CH2:8][N:9]([C:42]([C:39]2[CH:40]=[CH:41][C:36]([N:27]3[N:26]=[C:25]([C:18]4[CH:19]=[CH:20][C:21]([O:22][CH2:23][CH3:24])=[C:16]([O:15][CH2:13][CH3:14])[CH:17]=4)[C@@H:34]4[C@@H:29]([CH2:30][CH:31]=[CH:32][CH2:33]4)[C:28]3=[O:35])=[CH:37][CH:38]=2)=[O:43])[CH2:10][CH2:11]1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 84311-Piperazinecarboxylic acid, ethyl esterHCID 69641867HCID 69641867, compound

Product 1

HCID 69641980HCID 69641980, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Prepared from intermediate product A1 and 1-(ethoxycarbonyl)piperazine as described for compound 1. Cystallised from diethyl ether as the free base. M.p. 146–147° C.

Sources & evidence

ORD record
ord-0b9ae9bcc0de4be5bb429060df906c47
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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