4-(2-Piperazin-1-yl-ethyl)-morpholine → HCID 69642141, compound

HRID 1794184Notes

Reaction equation

HRID 1794184 reaction equation
[N:1]1([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[ClH:15].[CH3:16][O:17][C:18]1[C:26]2[O:25][C:24]([CH3:28])([CH3:27])[CH2:23][C:22]=2[C:21]([C:29]2[C@@H:38]3[C@@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([C:40]3[CH:45]=[CH:44][C:43]([C:46](N4CCN(C/C=C/C5C=CC=CC=5)CC4)=[O:47])=[CH:42][CH:41]=3)[N:30]=2)=[CH:20][CH:19]=1>>[ClH:15].[ClH:15].[CH3:16][O:17][C:18]1[C:26]2[O:25][C:24]([CH3:28])([CH3:27])[CH2:23][C:22]=2[C:21]([C:29]2[C@@H:38]3[C@@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([C:40]3[CH:45]=[CH:44][C:43]([C:46]([N:4]4[CH2:3][CH2:2][N:1]([CH2:7][CH2:8][N:9]5[CH2:10][CH2:11][O:12][CH2:13][CH2:14]5)[CH2:6][CH2:5]4)=[O:47])=[CH:42][CH:41]=3)[N:30]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 27346404-(2-Piperazin-1-yl-ethyl)-morpholineHCID 69642098HCID 69642098, compound

Product 1

HCID 69642141HCID 69642141, compound

Procedure

Prepared from intermediate product A2 and 4-(2-piperazin-1-yl-ethyl)-morpholine as described for compound 8. M.p. 271° C. (decomposes).

Sources & evidence

ORD record
ord-603209af0e444c769c8ecb2ad1da898f
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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