N,N-dimethyl-2-(piperazin-1-yl)acetamide → HCID 69642397, compound

HRID 1794185Notes

Reaction equation

HRID 1794185 reaction equation
[CH3:1][N:2]([CH3:12])[C:3](=[O:11])[CH2:4][N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1.[ClH:13].[CH3:14][O:15][C:16]1[C:24]2[O:23][C:22](C)(C)C[C:20]=2[C:19]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:43]=[CH:42][C:41]([C:44](N4CCN(C/C=C/C5C=CC=CC=5)CC4)=[O:45])=[CH:40][CH:39]=3)[N:28]=2)=[CH:18][CH:17]=1>>[ClH:13].[CH3:22][O:23][C:24]1[CH:20]=[C:19]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3[CH:39]=[CH:40][C:41]([C:44]([N:8]4[CH2:7][CH2:6][N:5]([CH2:4][C:3]([N:2]([CH3:12])[CH3:1])=[O:11])[CH2:10][CH2:9]4)=[O:45])=[CH:42][CH:43]=3)[N:28]=2)[CH:18]=[CH:17][C:16]=1[O:15][CH3:14]

Participants

3

Reactant 2

HCID 2758642N,N-dimethyl-2-(piperazin-1-yl)acetamideHCID 69642098HCID 69642098, compound

Product 1

HCID 69642397HCID 69642397, compound

Procedure

Prepared from intermediate product A6 and N,N-dimethyl-2-piperazin-1-yl-acetamide as described for compound 8. M.p. 93–94° C.

Sources & evidence

ORD record
ord-c232a6ae20ba41408cc1632a804e798d
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

Loading…