1-(Morpholinocarbonylmethyl)piperazine → HCID 69642455, compound

HRID 1794186Notes

Reaction equation

HRID 1794186 reaction equation
[N:1]1([C:7](=[O:15])[CH2:8][N:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[ClH:16].[CH3:17][O:18][C:19]1[C:27]2[O:26][C:25](C)(C)C[C:23]=2[C:22]([C:30]2[C@@H:39]3[C@@H:34]([CH2:35][CH:36]=[CH:37][CH2:38]3)[C:33](=[O:40])[N:32]([C:41]3[CH:46]=[CH:45][C:44]([C:47](N4CCN(C/C=C/C5C=CC=CC=5)CC4)=[O:48])=[CH:43][CH:42]=3)[N:31]=2)=[CH:21][CH:20]=1>>[ClH:16].[CH3:25][O:26][C:27]1[CH:23]=[C:22]([C:30]2[C@@H:39]3[C@@H:34]([CH2:35][CH:36]=[CH:37][CH2:38]3)[C:33](=[O:40])[N:32]([C:41]3[CH:42]=[CH:43][C:44]([C:47]([N:12]4[CH2:11][CH2:10][N:9]([CH2:8][C:7]([N:1]5[CH2:2][CH2:3][O:4][CH2:5][CH2:6]5)=[O:15])[CH2:14][CH2:13]4)=[O:48])=[CH:45][CH:46]=3)[N:31]=2)[CH:21]=[CH:20][C:19]=1[O:18][CH3:17]

Participants

3

Reactant 2

HCID 1006221-(Morpholinocarbonylmethyl)piperazineHCID 69642098HCID 69642098, compound

Product 1

HCID 69642455HCID 69642455, compound

Procedure

Prepared from intermediate product A6 and 1-morpholin-4-yl-2-piperazin-1-yl-ethanone as described for compound 8. M.p. 168–169° C.

Sources & evidence

ORD record
ord-a9148c9926694176b8c85d7e92dad3f4
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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