4-(2-Piperazin-1-yl-ethyl)-morpholine → HCID 69641798, compound

HRID 1794187Notes

Reaction equation

HRID 1794187 reaction equation
[N:1]1([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[ClH:15].[CH3:16][O:17][C:18]1[C:26]2[O:25][C:24]([CH3:28])([CH3:27])[CH2:23][C:22]=2[C:21]([C:29]2[C@@H:38]3[C@@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([C:40]3C=CC(C(N4CCN(C/C=C/C5C=CC=CC=5)CC4)=O)=CC=3)[N:30]=2)=[CH:20][CH:19]=1>>[ClH:15].[ClH:15].[CH3:16][O:17][C:18]1[C:26]2[O:25][C:24]([CH3:28])([CH3:27])[CH2:23][C:22]=2[C:21]([C:29]2[C@H:38]3[C@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([CH2:40][C:36]3[CH:37]=[CH:38][C:33]([C:32]([N:4]4[CH2:3][CH2:2][N:1]([CH2:7][CH2:8][N:9]5[CH2:10][CH2:11][O:12][CH2:13][CH2:14]5)[CH2:6][CH2:5]4)=[O:39])=[CH:34][CH:35]=3)[N:30]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 27346404-(2-Piperazin-1-yl-ethyl)-morpholineHCID 69642098HCID 69642098, compound

Product 1

HCID 69641798HCID 69641798, compound

Procedure

Prepared from intermediate product A11 and 4-(2-piperazin-1-yl-ethyl)-morpholine as described for compound 8. M.p. 210–211° C.

Sources & evidence

ORD record
ord-9270daabbcf647fd82176b4d2ba32ea3
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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