1-((Pyrrolidine-1-carbonyl)methyl)piperazine → HCID 69642219, compound

HRID 1794188Notes

Reaction equation

HRID 1794188 reaction equation
[N:1]1([CH2:7][C:8]([N:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:9])[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[ClH:15].[CH3:16][O:17][C:18]1[C:26]2[O:25][C:24](C)(C)C[C:22]=2[C:21]([C:29]2[C@@H:38]3[C@@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([C:40]3[CH:45]=[CH:44][C:43]([C:46](N4CCN(C/C=C/C5C=CC=CC=5)CC4)=[O:47])=[CH:42][CH:41]=3)[N:30]=2)=[CH:20][CH:19]=1>>[ClH:15].[CH3:24][O:25][C:26]1[CH:22]=[C:21]([C:29]2[C@@H:38]3[C@@H:33]([CH2:34][CH:35]=[CH:36][CH2:37]3)[C:32](=[O:39])[N:31]([C:40]3[CH:41]=[CH:42][C:43]([C:46]([N:4]4[CH2:3][CH2:2][N:1]([CH2:7][C:8](=[O:9])[N:10]5[CH2:11][CH2:12][CH2:13][CH2:14]5)[CH2:6][CH2:5]4)=[O:47])=[CH:44][CH:45]=3)[N:30]=2)[CH:20]=[CH:19][C:18]=1[O:17][CH3:16]

Participants

3

Reactant 2

HCID 1006141-((Pyrrolidine-1-carbonyl)methyl)piperazineHCID 69642098HCID 69642098, compound

Product 1

HCID 69642219HCID 69642219, compound

Procedure

Prepared from intermediate product A6 and 2-piperazin-1-yl-1-pyrrolidin-1-yl-ethanone as described for compound 8. M.p. 160–161° C.

Sources & evidence

ORD record
ord-7a02eec967f34aeb8780dd1fd3bf1888
Source dataset
uspto-grants-2006_04
Patent number
US07022696B2

Reaction notes

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