1-Piperazinylpyrazine → HCID 86759959, compound

HRID 1794189Notes

Reaction equation

[N:1]1([C:7]2[CH:12]=[N:11][CH:10]=[CH:9][N:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[ClH:13].[CH3:14][O:15][C:16]1[C:24]2[O:23][C:22]([CH3:26])([CH3:25])[CH2:21][C:20]=2[C:19]([C:27]2[C@@H:36]3[C@@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([C:38]3C=CC(C(N4CCN(C/C=C/C5C=CC=CC=5)CC4)=O)=CC=3)[N:28]=2)=[CH:18][CH:17]=1>>[ClH:13].[ClH:13].[CH3:14][O:15][C:16]1[C:24]2[O:23][C:22]([CH3:26])([CH3:25])[CH2:21][C:20]=2[C:19]([C:27]2[C@H:36]3[C@H:31]([CH2:32][CH:33]=[CH:34][CH2:35]3)[C:30](=[O:37])[N:29]([CH2:38][C:34]3[CH:35]=[CH:36][C:31]([C:30]([N:4]4[CH2:5][CH2:6][N:1]([C:7]5[CH:12]=[N:11][CH:10]=[CH:9][N:8]=5)[CH2:2][CH2:3]4)=[O:37])=[CH:32][CH:33]=3)[N:28]=2)=[CH:18][CH:17]=1

Participants

Reactant 2

HCID 27346391-Piperazinylpyrazine

HCID 69642098HCID 69642098, compound

Product 1

HCID 86759959HCID 86759959, compound

Procedure

Prepared from intermediate product A11 and 3,4,5,6-Tetrahydro-2H-[1,2′]bipyrazinyl as described for compound 8. M.p. 124–126° C.

Sources & evidence

ORD record: ord-9a382e73636d4dcd9e49e4c990b1235d
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07022696B2

Reaction notes

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