4-Chloroindole → HCID 10184101, compound

HRID 1794196Notes

Reaction equation

HRID 1794196 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[F:11][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=O)=[C:14]([C:20]([F:23])([F:22])[F:21])[CH:13]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:16]([C:4]1[C:3]3[C:7](=[CH:8][CH:9]=[CH:10][C:2]=3[Cl:1])[NH:6][CH:5]=1)[C:15]1[CH:18]=[CH:19][C:12]([F:11])=[CH:13][C:14]=1[C:20]([F:23])([F:22])[F:21])=[CH:5][NH:6]2

Participants

3

Reactant 2

HCID 913454-ChloroindoleHCID 5229404-Fluoro-2-(trifluoromethyl)benzaldehyde

Product 1

HCID 10184101HCID 10184101, compound

Procedure

The compound Bis(4-chloroindol-3-yl)-(4-fluoro-2-trifluoromethylphenyl)methane was prepared following procedure A, starting from 4-chloro indole and 4-fluoro-2-(trifluromethyl) benzaldehyde. LC: Tr 2.52 min, MS: 477 (M+H)+

Workup

  1. customTr 2.52 min, MS

Sources & evidence

ORD record
ord-2c99f625088440f4bd61be3bf8f7ccf5
Source dataset
uspto-grants-2006_04
Patent number
US07022730B2

Reaction notes

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