3-Bromopyridine → HCID 69895778, compound

Participants

Reaction Steps

Prepared in a similar manner to Example 7 from 3-(5-methyl-3-phenylisoxazol-4-yl)-9-bromo-5H-[1,2,4]triazolo[3,4-a]isoindole (100 mg) (prepared using 7-bromo-2,3-dihydroisoindol-1-one by analogy with Example 4) and 3-bromopyridine (0.06 ml) to give the title compound (7 mg, 3%). 1H NMR (360 MHz, CDCl3) δ 8.90 (1H, s), 8.71 (1H, s), 8.40 (1H, d, J=5.8 Hz), 7.56–7.40 (8H, m), 7.30 (1H, d, J=7.3 Hz), 4.08 (2H, s), 2.68 (3H, s), miz (ES+) 392 (M+H)+.

Provenance & Evidence