Acetaldehyde → HCID 11277400, compound

HRID 1794563Notes

Reaction equation

[C:1]([N:5]1[C@@H:9]([CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][O:7][C:6]1=[O:17])(=[O:4])[CH2:2][CH3:3].[CH:18](=[O:20])[CH3:19]>>[CH3:3][C@@H:2]([C@H:18]([OH:20])[CH3:19])[C:1]([N:5]1[C@@H:9]([CH2:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH2:8][O:7][C:6]1=[O:17])=[O:4]

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 2733696(4S)-4-Benzyl-3-propanoyl-1,3-oxazolidin-2-one

Product 1

HCID 11277400HCID 11277400, compound

Procedure

Prepared from (4S)-N-propionyl-4-benzyl-2-oxazolidinone and acetaldehyde according to the procedure described in Example 1, paragraph A. 1H-NMR (360 MHz, CDCl3): δ 7.2–7.4 (m,5H); 4.71 (m,1H); 4.12–4.25 (m,2H); 3.76 (dq,1H); 3.26 (dd,1H); 2.79 (dd,1H); 1.30 (d,3H), 1.21 (d,3H).

Sources & evidence

ORD record: ord-e15b5e55f30b4f86a5f845461820c251
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07022825B2

Reaction notes

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