Cyclohexanone → HCID 22222164, compound

HRID 1794576Notes

Reaction equation

HRID 1794576 reaction equation
[C:1]([N:5]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[O:7][C:6]1=[O:14])(=[O:4])[CH2:2][CH3:3].[C:15]1(=[O:21])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[OH:21][C:15]1([CH:2]([CH3:3])[C:1]([N:5]2[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[O:7][C:6]2=[O:14])=[O:4])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 7967CyclohexanoneHCID 8437913-Propionyl-2-benzoxazolinone

Product 1

HCID 22222164HCID 22222164, compound

Procedure

Prepared according to the method of paragraph C by reaction of N-propionyl-2-benzoxazolone with cyclohexanone; mp 58–9° C. 1H NMR (CDCl3): δ 8.09 (m, 1 H); 7.25 (m, 3 H); 4.11 (q, 1 H, J=7 Hz); 2.90 (br s, 1 H); 1.82 (br d, 1 H, J=13 Hz); 1.59 (m, 8 H); 1.34 (d, 3 H, J=7 Hz); 1.23 (m, 1 H). 13C NMR (CDCl3): δ 177.20, 151.42, 142.03, 127.69, 125.55, 124.91, 116.38, 109.88, 72.89, 46.77, 37.03, 33.37, 25.64, 21.73, 21.40, 12.16.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a23dd4906ada4bbbb271bd57ddc86b83
Source dataset
uspto-grants-2006_04
Patent number
US07022825B2

Reaction notes

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