Triethylamine → HCID 21022372, compound

Participants

Reaction Steps

A reaction mixture of 33 (350 mg, 0.74 mmol), 4-chlorobenzoyl chloride (390 mg, 2.29 mmol) and Et3N (412 μl, 2.96 mmol) in CH2Cl2 was stirred at room temperature for 14 h. The mixture was purified by silica gel column directly to give 34 (301 mg, 67%). 34 had an analytical HPLC retention time=4.41 min. (Column: YMC S5 Combiscreen 4.6×50 mm (4 min.); Solvent A=10% MeOH, 90% H2O, 0.2% H3PO4; Solvent B=90% MeOH, 10% H2O, 0.2% H3PO4).

Provenance & Evidence