Ammonia → HCID 22222280, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 32 (160 mg, 0.42 mmol) and 7N ammonia in MeOH (7.5 mL) was heated in a sealed tube at 120° C. for 2 h, and cooled to room temperature. Solvent was removed to give a yellow solid 36 (136 mg, 100%), which was used without further purification. 1H-NMR (400 MHz, CDCl3): δ 7.07–7.28 (m, 5H), 5.39 (s 2H), 4.23 (brs, 2H), 4.15 (t, J=5.99 Hz, 1H), 2.72 (s, 3H), 1.46–1.66 (m, 2H), 0.75 (t, J=7.37 Hz, 3H).

Provenance & Evidence