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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1794810Generated: October 26, 2026

Methyl 1-aminocyclopropane-1-carboxylate hydrochloride → Methyl 1-[4-(4-oxo-piperidin-1-yl)-benzoylamino]-cyclopropanecarboxylate

https://huagongshe.com/reaction/1794810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1-aminocyclopropane-1-carboxylate hydrochlorideHCID 12760695—
Reactant4-(4-Oxopiperidin-1-yl)benzoic acidHCID 22064022—
ProductMethyl 1-[4-(4-oxo-piperidin-1-yl)-benzoylamino]-cyclopropanecarboxylateHCID 22220461—

Reaction Steps

The title compound was prepared from 4-(4-oxo-piperidin-1-yl)-benzoic acid (which was obtained in Example 151) and 1-aminocyclopropane-1-carboxylic acid methyl ester hydrochloride according to the procedure of Example 154 as a gum; MS (ES) m/z; 317.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07022716B2
Source datasetuspto-grants-2006_04
ORD IDord-29f39c5303c64c3cba3c6f367acfd15a
Source noteuspto-grants-2006_04