HCID 10354678, compound → HCID 69654808, compound

Participants

Reaction Steps

The title compound was prepared from benzyloxycarbonylmethylsulfonylchloride (J. Antibiot., 1994, 47, 1041) and 1-(4-amino-phenyl)-piperidin-4-one (which was obtained in Example 224) according to the procedure B of Example 225 as a white solid; 1H NMR (300 MHz, DMSO-d6) δ 2.42 (t, J=6.0 Hz, 4 H), 3.55 (t, J=6.0 Hz, 4 H), 4.16 (s, 2 H), 5.16 (s, 2 H), 6.99 (d, J=9.0 Hz, 2 H), 7.10 (d, J=9.0 Hz, 2 H), 9.73 (s, 1 H); MS (ES) m/z: 403.2 (MH+); HRMS Calcd. for C20H22N2O5S(M+): 402.1250. Found: 402.1237.

Provenance & Evidence