HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloro-4-(2-chloro-4-nitrophenoxy)benzene-1-sulfonyl chloride → HCID 69654662, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloro-4-(2-chloro-4-nitrophenoxy)benzene-1-sulfonyl chloride | HCID 2774361 | — |
| Reactant | 4-((2S)-3-Amino-2-hydroxy-propoxy)-1,3-dihydrobenzoimidazol-2-one | HCID 10799105 | — |
| Reactant | 1-(4-Amino-phenyl)-piperidin-4-one hydrochloride | HCID 22220240 | — |
| Product | HCID 69654662 | HCID 69654662 | — |
Reaction Steps
The title compound was prepared from 1-(4-aminophenyl)-4-piperidone hydrochloride (which was obtained in Example 224), 4-(2-chloro-4-nitrophenoxy)-3,5-dichlorobenzenesulfonyl chloride, and (S)-4-[2-hydroxy-3-aminopropoxy]-1,3-dihydro-2H-benzimidazol-2-one (U.S. Pat. No. 5,786,356/1998) according to the procedure of Example 346; MS (ES) m/z: 777.2, 779.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07022716B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-3d8dc479d8a54ee98a85ad86fc4a81f0 |
| Source note | uspto-grants-2006_04 |