Ethyl isocyanatoacetate → HCID 86584575, compound

HRID 1794919Notes

Reaction equation

[N:1]([CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])=[C:2]=[O:3].[CH2:10]([NH:14][C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH2:26][CH2:25][C:24](=[O:27])[CH2:23][CH2:22]2)=[CH:17][CH:16]=1)[CH2:11][CH2:12][CH3:13]>>[CH2:10]([N:14]([C:2]([NH:1][CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])=[O:3])[C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH2:26][CH2:25][C:24](=[O:27])[CH2:23][CH2:22]2)=[CH:17][CH:16]=1)[CH2:11][CH2:12][CH3:13]

Participants

Reactant 2

HCID 76283Ethyl isocyanatoacetate

HCID 22220234HCID 22220234, compound

Product 1

HCID 86584575HCID 86584575, compound

Procedure

The title compound was prepared from ethyl isocyanatoacetate and 1-[4-(butylamino)phenyl]-4-piperidinone (which was obtained in Example 364) according to the procedure of Example 366 as a pale brown solid; MS (ES) m/z: 376.5 (MH+).

Sources & evidence

ORD record: ord-956244551b554a67957757587f8cc30a
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07022716B2

Reaction notes

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