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HRID1794954

反应详情

EQUATION

反应方程式

HRID 1794954 的结构方程式

REACTANTS

反应物

2
结构：Cc1cn(CC(=O)O)c(=O)[nH]c1=O
HCID853753

Thymine-1-acetic acid

C7H8N2O4

结构：Cl.O=C1CNCCN1S(=O)(=O)c1c(Cl)cc(Cl)cc1[N+](=O)[O-]
HCID68802329

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cn(CC(=O)N2CCN(S(=O)(=O)c3c(Cl)cc(Cl)cc3[N+](=O)[O-])C(=O)C2)c(=O)[nH]c1=O
HCID22222429

未命名化合物

收率 88.3%

PROCEDURE

实验过程

The title compound (919 mg, 88%) was synthesized by reaction of 1-(4,6-dichloro-2-nitro-benzenesulfonyl)-piperazin-2-one HCl salt (781 mg, 2.0 mmol) with (thymin-1-yl)-acetic acid (368 mg, 2.0 mmol) as per the procedure of example 64. 1H-NMR (500 MHz; DMSO-d6) δ 11.34 (s, 0.6H), 11.32 (s, 0.4H), 8.42 (d, 0.4H), 8.41 (d, 0.6H), 8.32 (d, 0.4H), 8.30 (d, 0.6H), 7.35 (s, 0.6H), 7.27 (s, 0.4H), 4.69 (s, 1.2H), 4.58 (s, 0.8H), 4.42 (s, 0.8H), 4.27 (s, 1.2H), 4.11 (t, 1.2H), 3.97 (t, 0.8H), 3.93 (t, 1.2H), 3.82 (t, 0.8H), 1.74 (s, 3H).