HRID1794958

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)Cn1ccc(NC(=O)OC(c2ccccc2)c2ccccc2)nc1=O

HCID15513042

[4-{[(Diphenylmethoxy)carbonyl]amino}-2-oxopyrimidin-1(2H)-yl]acetic acid

C20H17N3O5

结构：Cl.O=C1CNCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-]

HCID68802440

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1ccn(CC(=O)N2CCN(S(=O)(=O)c3ccccc3[N+](=O)[O-])C(=O)C2)c(=O)n1)OC(c1ccccc1)c1ccccc1

HCID22222435

未命名化合物

收率 195.6%

PROCEDURE

实验过程

The title compound (2.53 g, 78%) was synthesized by reaction of 1-(2-nitro-benzenesulfonyl)-piperazin-2-one HCl salt (679 mg, 2.0 mmol) with [4-N-(benzhydryloxycarbonyl)-cytosin-1-yl]-acetic acid (1.90 g, 5.0 mmol) as per the procedure of example 77.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a2c59c31c7bc4735bef398887d646703
来源数据集: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07022851B2
来源说明: uspto-grants-2006_04

反应 SMILES

Cl.[N+:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[S:11]([N:14]1[CH2:19][CH2:18][NH:17][CH2:16][C:15]1=[O:20])(=[O:13])=[O:12])([O-:4])=[O:3].[CH:21]([O:34][C:35]([NH:37][C:38]1[CH:43]=[CH:42][N:41]([CH2:44][C:45](O)=[O:46])[C:40](=[O:48])[N:39]=1)=[O:36])([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH:21]([O:34][C:35]([NH:37][C:38]1[CH:43]=[CH:42][N:41]([CH2:44][C:45]([N:17]2[CH2:18][CH2:19][N:14]([S:11]([C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=3[N+:2]([O-:4])=[O:3])(=[O:12])=[O:13])[C:15](=[O:20])[CH2:16]2)=[O:46])[C:40](=[O:48])[N:39]=1)=[O:36])([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1