Aluminium lithium hydride → HCID 11097747, compound

Participants

Reaction Steps

To a solution of N-methoxy-N-methyl-2-{[(4-methylphenyl)sulfonyl]methyl}benzamide (0.645 mmol) in 5 mL THF at −78° C. is added 1.0 M solution of LiAlH4 in THF (0.709 mmol) slowly with stirring. The reaction is stirred at −78° C. for 1 hr and gradually warmed up to RT. The reaction mixture is diluted with EtOAc and washed with H2O. The solution is dried over Na2SO4 and the solvent is evaporated to give a quantitative yield of 2-{[(4-methylphenyl)sulfonyl]methyl}benzaldehyde.

Provenance & Evidence