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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1795136Generated: October 30, 2026

Potassium Carbonate → HCID 22185760, compound

https://huagongshe.com/reaction/1795136

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant5-(Chloromethyl)-2-(trifluoromethyl)pyridineHCID 2773810—
Reactant2-(3,3,3-Trifluoropropyl)malononitrileHCID 22185761—
SolventDimethylformamideHCID 6228—
ProductHCID 22185760HCID 2218576079.1%

Reaction Steps

By using (3,3,3-trifluoropropyl)malononitrile (83 mg), N,N-dimethylformamide (10 ml), potassium carbonate (71 mg) and 3-(chloromethyl)-6-(trifluoromethyl)pyridine (100 mg) according to the similar method described in Production Example 4 was obtained 130 mg of 2-((6-(trifluoromethyl)-3-pyridyl)methyl)-2-(3,3,3-trifluoropropyl)malononitrile represented by the following formula (hereinafter referred to as the present invention compound (9)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07026340B2
Source datasetuspto-grants-2006_04
ORD IDord-9541b9931db74deab1345b0350bf3717
Source noteuspto-grants-2006_04