HCID 21023794, compound → HCID 21023793, compound

HRID 1795153Notes

Reaction equation

HRID 1795153 reaction equation
Cl[C:2]1C=CC(C2N=C(C(C)(C)CNC)NC=2C2C=CN=CC=2)=CC=1O.[Cl:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[N:34]=[C:35]([C:44]([CH3:60])([CH3:59])[CH2:45][NH:46][C:47]([N:49]3[CH2:54][CH2:53][N:52]([CH2:55][CH2:56][O:57][CH3:58])[CH2:51][CH2:50]3)=[O:48])[NH:36][C:37]=2[C:38]2[CH:43]=[CH:42][N:41]=[CH:40][CH:39]=2)=[CH:29][C:28]=1[OH:61]>>[Cl:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[N:34]=[C:35]([C:44]([CH3:59])([CH3:60])[CH2:45][N:46]([CH3:2])[C:47]([N:49]3[CH2:50][CH2:51][N:52]([CH2:55][CH2:56][O:57][CH3:58])[CH2:53][CH2:54]3)=[O:48])[NH:36][C:37]=2[C:38]2[CH:43]=[CH:42][N:41]=[CH:40][CH:39]=2)=[CH:29][C:28]=1[OH:61]

Participants

3

Reactant 2

HCID 21023794HCID 21023794, compoundHCID 22185493HCID 22185493, compound

Product 1

HCID 21023793HCID 21023793, compoundYield 41%

Procedure

The title compound (170 mg, 41%) was prepared from the product of Example 52 and the product of Example 49 Step 1 using the method described in Example 49 Step 2; MS(ES+) m/e 527/529 [M+H]+.

Sources & evidence

ORD record
ord-92b6025e9b194ffc8ee06a551c15818e
Source dataset
uspto-grants-2006_04
Patent number
US07026336B1

Reaction notes

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