HCID 9955730, compound → HCID 22185373, compound

HRID 1795154Notes

Reaction equation

HRID 1795154 reaction equation
C(OC(=O)N[CH2:8][C:9]([C:12]1[NH:13][C:14]([C:26]2[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=2)=[C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[C:19]([O:24]C)[CH:18]=2)[N:16]=1)(C)[CH3:10])(C)(C)C.C(OC([NH:40]C(C)(C)C=O)=O)(C)(C)C>>[NH2:40][C:9]([C:12]1[NH:13][C:14]([C:26]2[CH:27]=[CH:28][N:29]=[CH:30][CH:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[C:19]([OH:24])[CH:18]=2)[N:16]=1)([CH3:10])[CH3:8]

Participants

3

Reactant 2

HCID 9955730HCID 9955730, compoundHCID 14578674tert-butyl N-(2-methyl-1-oxopropan-2-yl)carbamate

Product 1

HCID 22185373HCID 22185373, compound

Procedure

The title compound was prepared from the product of Example 1, Step 3 and 2-tert-butoxycarbonylamino-2-methylpropanal (T. Seki et al., Chem. Pharm. Bull.; 1996, 44, 2061) using the methods described in Example 1 Step 4, followed by those of Example 2 and Example 3; MS(ES+) m/e 329/331 [M+H]+.

Sources & evidence

ORD record
ord-d773a12701624927937b0a84c3d83f19
Source dataset
uspto-grants-2006_04
Patent number
US07026336B1

Reaction notes

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