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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 179541Generated: October 25, 2026

Chloride → 3-[4-(Pyridin-2-yl-oxy)phenyl]-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/179541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantPotassium CationHCID 813—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
ReactantLithium ionHCID 28486—
Reactant8-Boc-3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-eneHCID 22648094—
Reactant2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]pyridineHCID 67248701—
Product3-[4-(Pyridin-2-yl-oxy)phenyl]-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylic acid tert-butyl esterHCID 67412498—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-635e7b1729e94eddac868a85c121d346
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)