Ethyl 4-bromobenzoate → HCID 21024363, compound

HRID 1795601Notes

Reaction equation

HRID 1795601 reaction equation
[CH2:1]([C:3]1[C:4]2[CH:5]=[CH:6][C:7]([NH2:15])=[CH:8][C:9]=2[C:10]([CH3:14])([CH3:13])[CH2:11][CH:12]=1)[CH3:2].Br[C:17]1[CH:27]=[CH:26][C:20]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:19][CH:18]=1>>[CH2:24]([O:23][C:21](=[O:22])[C:20]1[CH:26]=[CH:27][C:17]([NH:15][C:7]2[CH:6]=[CH:5][C:4]3[C:3]([CH2:1][CH3:2])=[CH:12][CH2:11][C:10]([CH3:14])([CH3:13])[C:9]=3[CH:8]=2)=[CH:18][CH:19]=1)[CH3:25]

Participants

3

Reactant 2

HCID 22043Ethyl 4-bromobenzoateHCID 22218253HCID 22218253, compound2×

Product 1

HCID 21024363HCID 21024363, compound

Procedure

Following General Procedure L, 5-ethyl-8,8-dimethyl-7,8-dihydro-naphthalen-2-ylamine (Compound 72, 0.17 g, 0.85 mmol), was reacted with ethyl 4-bromobenzoate to give the title compound as a yellow solid.

Sources & evidence

ORD record
ord-18b1277cd97e464d8f757f5964e8befa
Source dataset
uspto-grants-2006_04
Patent number
US07026487B2

Reaction notes

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