Potassium Hydroxide → HCID 69659124, compound

HRID 1795609Notes

Reaction equation

C([N:3]([C:15]1[C:24]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:23][C:22]2[C:21]([CH3:33])([CH3:32])[CH2:20][CH:19]=[C:18]([CH3:34])[C:17]=2[CH:16]=1)[C:4]1[CH:14]=[CH:13][C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:6][CH:5]=1)C.[OH-].[K+]>>[CH2:26]([O:25][C:24]1[C:15]([NH:3][C:4]2[CH:5]=[CH:6][C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:13][CH:14]=2)=[CH:16][C:17]2[C:18]([CH3:34])=[CH:19][CH2:20][C:21]([CH3:33])([CH3:32])[C:22]=2[CH:23]=1)[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 22218336HCID 22218336, compound2×

Product 1

HCID 69659124HCID 69659124, compoundYield 27%

Procedure

Following General Procedure E ethyl 4-[ethyl-(3-n-hexyloxy-5,5,8-trimethyl-5,6-dihydronaphthalen-2-yl)amino]benzoate (Compound 125, 0.036 g, 0.078 mmol) was saponified with KOH to give 0.0090 g (27%) of the title compound as a yellow oil.

Sources & evidence

ORD record: ord-d5b3925ebcb14910b0763c8e43da8708
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07026487B2

Reaction notes

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