HCID 21024022, compound → HCID 21024014, compound

HRID 1795684Notes

Reaction equation

[CH2:1]([O:3][CH2:4][C:5]([CH2:7][C:8]([OH:10])=[O:9])=[O:6])[CH3:2].[C:11]([O:14][CH:15]1[C:16]([O:53]C(OCC)C)([CH3:52])[CH2:17][CH2:18][CH:19](O)[CH2:20][C:21]([O:23][CH:24](/[C:29](/[CH3:50])=[CH:30]/[CH:31]=[CH:32]/[CH:33]([CH3:49])[CH2:34][CH:35]2[O:48][CH:36]2[CH:37]([CH3:47])[CH:38]([O:41]C(OCC)C)[CH2:39][CH3:40])[CH:25]([CH3:28])[CH:26]=[CH:27]1)=[O:22])(=[O:13])[CH3:12]>>[C:11]([O:14][CH:15]1[C:16]([OH:53])([CH3:52])[CH2:17][CH2:18][CH:19]([O:9][C:8](=[O:10])[CH2:7][C:5](=[O:6])[CH2:4][O:3][CH2:1][CH3:2])[CH2:20][C:21]([O:23][CH:24](/[C:29](/[CH3:50])=[CH:30]/[CH:31]=[CH:32]/[CH:33]([CH3:49])[CH2:34][CH:35]2[O:48][CH:36]2[CH:37]([CH3:47])[CH:38]([OH:41])[CH2:39][CH3:40])[CH:25]([CH3:28])[CH:26]=[CH:27]1)=[O:22])(=[O:13])[CH3:12]

Participants

Reactant 2

HCID 21024022HCID 21024022, compound

HCID 21798992HCID 21798992, compound

Product 1

HCID 21024014HCID 21024014, compound

Procedure

Ethoxyacetylacetic acid was esterified with (8E,12E,14E)-7-acetoxy-6,21-bis(1-ethoxyethoxy)-3-hydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide through the similar synthetic route as Example B24, to give the title compound as a colorless oil.

Sources & evidence

ORD record: ord-3ed7198584bc4960a0257f5bc5f6a33e
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07026352B1

Reaction notes

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