HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaminophen → N-[4-(3-Amino-4-nitrophenoxy)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaminophen | HCID 1983 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-(4-Hydroxyphenylsulphanyl)-2-amino-nitrobenzene | HCID 22180683 | — |
| Product | N-[4-(3-Amino-4-nitrophenoxy)phenyl]acetamide | HCID 13705240 | — |
Reaction Steps
4-(4-Acetylaminophenoxy)-2-amino-nitrobenzene (46.57 g) was prepared from 4-acetylaminophenol (30.2 g; 0.2 mol) using the general method described for 4-(4-hydroxyphenylsulphanyl)-2-amino-nitrobenzene in Example 2, except that one equivalent of NaH was used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030123B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-40c96a8e143b487dbd6ff38eb3453fdd |
| Source note | uspto-grants-2006_04 |